2015年8月20日星期四

Is Stage 2 Membranous Glomerulonephritis Serious


Is Stage 2 Membranous Glomerulonephritis Serious
Many patients with Stage 2 Membranous Glomerulonephritis(MN) believe that stage 2 MN means that this disease has progressed into the end stage, and they believe that in the Stage 2 MN, there are not any treatments available, so what they can do is just to wait for the end of their life. Is their thought right?
The answer is no! In fact, from the perspective of pathology, MN could divide into five stages: I stage to Ⅴ stage. Stage 2 MN relatively lies in the early and mid term stage of the disease. So, after the normalized treatment, the patients are hopeful to reach the level of clinical cure.

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Here the clinical cure in deed has some difference with the patients’ completely rehabilitation level we usually refer to. Clinical cure means that the patients’ clinical symptoms all disappear, and some abnormal indexes will improve and by the use of medicines, patients will also reach up to same result as normal healthy persons.
The stages of MN are divided according to the severity degree of the disease. Generally speaking, the MN is displayed mainly in the form of Nephrotic Syndrome(NS) and Asymptomatic Proteinuria.
Stage 2 MN also refers the stage of the formation of spikes, and the glomerulus reactive proliferation against those deposited immune complexes, and etc.
As for the treatment of Stage 2 MN, treatment plans are often formulated according to the patients’ specific conditions. If the patient shows up the clinical manifestation of swelling with diagnosis of NS-typed MN, this time we should use western medicines, especially hormones, to treat the symptoms, thus we could eliminate those symptoms such as edema, proteinuria, etc.
Although hormones are usually effective in eliminating those apparent symptoms, however, these purely symptomatic treatment means will not satisfy patients, because that would lead to the patients’ diseases’ relapse.
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So in order to treat this disease, we propose Immunotherapy to treat Stage 2 Membranous Glomerulonephritis. It is really not a serious disease.

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